Dopamine science

Submitted by Crow on
Printer-friendly version

If anyone doubts the addictiveness, the dopamine rollercoaster, etc......take a look at patients who need dopamine therapy and see what happens to them.

We are the lucky ones who have the option of working towards balance naturally.

These Parkinson's folks are dealing with it to stay alive!

See side effects.........

Unlike a resting tremor (a clear sign of dysfunction in the nervous system), sex, gambling and shopping are common actions in everyday life. Thus, problematic behaviors may not be instantly viewed as abnormal, even when they begin to present a deviation from the person's usual character. Hypersexual behaviors range from intrusive sexual thoughts, urges or remarks, to overt, inappropriate and often offensive sexual behaviors. Not surprisingly, the scale of such aberrant behaviors will vary from person to person. There may be increased demands for sexual activity in an established context or attempts at indiscriminate sexual activity in random contexts. Some patients continually make inappropriate remarks in public while others - in a departure from previous behaviors - may begin to use pornography, patronize prostitutes, engage in Internet-based sexual activity or develop paraphilias (intense, sexually arousing fantasies, urges or behaviors such as exhibitionism, cross-dressing or sado-masochism). These forms of hypersexuality may be accompanied by such disruptive experiences as irritability, anger, mood instability and disturbed sleep.

Abuse of anti-parkinsonian medications
Abuse of anti-parkinsonian medications is another impulse-control disorder that can occur in people with PD. It consists of a pattern of inappropriate and excessive use of anti-parkinsonian medications along with drug-seeking behaviors, tolerance and psychological dependence. Even early in the course of their Parkinson's, affected patients will insist upon increases in dopaminergic medications to treat "unbearable" motor symptoms as well as psychological feelings. Increasingly, patients have a distorted view of "on-off" motor and mental states - that is, they describe an intense "high" and increased energy or well-being in the "on" state and irritability, anxiety, or even despair or suicidality in the "off" state. Often, these patients report a history of a mood disorder before the onset of PD and its treatment.

Sound Familiar?


Sure does

Thanks for posting this. We cite a lot of the research behind this in our book, and in some of our articles. It's very telling, if you ask us.

Shows how innocently someone can go off the rails simply by dysregulating dopamine. And because our reward circuitry is our "inner compass," it's very hard not to conclude that "I'm fine. It's the rest of the world that just doesn't get it." Wink

Whoever wrote that didn't mention that these patients also experience changes in sexual orientation, cross-dressing, desire for anal sex, etc....which fades when their meds are sorted out.